Malignant Melanoma and Its Stromal Nonimmune Microecosystem
Journal of Oncology, 06/29/2012
Pierard GE et al. – The cutaneous malignant melanoma (CMM)–stroma connection appears crucial to the growth regulation, invasiveness and initial metastatic spread of CMM cells. Although much remains to be learned in this field, the active intervention of the peri–CMM stroma is likely involved in the inconspicuous early metastatic migration of CMM cells.