Modelling the cost-effectiveness of strategies to prevent tuberculosis in child contacts in a high-burden setting
Mandalakas AM et al. – Screening for M tuberculosis infection and provision of isoniazid preventive therapy (IPT) in young children is a highly cost–effective intervention. Screening without testing for M tuberculosis infection is the most cost–effective strategy in 0–2–year–old children and the preferred strategy in 3–5–year–old children. Lack of testing capacity should therefore not be a barrier to IPT delivery. These findings highlight the cost effectiveness of contact tracing and IPT delivery in young children exposed to TB in high–burden countries.