Using Donor-Specific Antibodies to Monitor the Need for Immunosuppression
Hoshino J et al. – Donor–specific antibodies (DSA) monitoring is highly effective for detecting escape from tolerance and reemergence of the immune response in weaned patients. DSA appearance was inversely proportional to the level of maintenance drugs in the weaning process. Measurement of DSA on a monthly basis is adequate for detection of the change in immune reactivity.