3-Demethyldihydromaldoxin and dihydromaldoxin, two anti-inflammtory diaryl ethers from a Steganospora species
The Journal of Antibiotics, 06/14/2012
Schreiber D et al. – Compounds (1) and (2) inhibited lipopolysaccharide (LPS)/interferon–γ (IFN–γ)–induced CXCL10 promoter activity in transiently transfected MM6 cells in a dose–dependent manner with IC50 values of 39–41 μM and also reduced LPS/IFN–γ–induced CXCL10 protein synthesis and excretion.



