Renal function in patients with β-thalassaemia major: a long-term follow-up study
Nephrology Dialysis Transplantation, 06/14/2012
Lai ME et al. – In most adults with thalassaemia major (TM), the estimated glomerular filtration rate (eGFR) tends to remain within a normal range after 10 years. However, patients with elevated phosphaturia, elevated uricuria and/or abnormal levels of calcaemia show a significant decline in eGFR over time, suggesting that tubular damage acquired in childhood caused by either TM or its treatment may eventually result in abnormal eGFR.