Brain metastases during follow-up of children and adolescents with extracranial malignant germ cell tumors: Risk adapted management decision tree analysis based on data of the MAHO/MAKEI-registry
Pediatric Blood & Cancer, 06/21/2012
Gobel U et al. – A high–risk subgroup is detected with a decision tree analysis approach. These patients may benefit from an intensified chemotherapy. Close surveillance for CNS–metastases is warranted in this high–risk group while less close monitoring in low–risk patients is justified.