Mixed Echoic Thyroid Nodules on Ultrasound: Approach to Management Full Text
Yonsei Medical Journal, 06/14/2012
Sohn YM et al. – Mixed echoic nodules with no suspicious ultrasound (US) features and benign cytology can be followed up using US, as they revealed very low malignancy rates, even if they showed growth on follow–up US.Methods
- Among patients who underwent US–guided fine needle aspiration biopsy, 316 mixed echoic nodules in 303 patients were included after excluding the patients with pure solid or cystic nodules or without further cytopathologic evaluation.
- The authors evaluated malignancy risk according to US features and changes in size and shape on follow–up US.
- The malignancy rate was 31.6% (6 of 19) for nodules with suspicious US features and 2.7% (8 of 297) for nodules without suspicious US features (p<0.001).
- Among 265 nodules with no suspicious US features and initial benign cytology, 15 nodules with suspicious US change and decreased size, 25 nodules with no suspicious US change and increased size, and 225 nodules with no suspicious US change and no change in size were observed on follow–up USs.
- The malignancy risk thereof was 0%, 0% and 0.4%, respectively (p=1.000).