Desmin and CD34 positivity in cellular fibrous histiocytoma: an immunohistochemical analysis of 100 cases.
Journal of Cutaneous Pathology, 06/26/2012
Volpicelli ER et al. – Frequent desmin (32%) and occasional CD34 (6%) expression are encountered in Cellular benign fibrous histiocytoma (CBFH). Desmin positivity can be explained on the basis of myofibroblastic differentiation. The occasional CD34 positivity in a subset of CBFH should not be a deterrent from making the correct pathologic diagnosis, based on characteristic morphologic features.