Supra-additive expression of interleukin-6, interleukin-8 and basic fibroblast growth factor in vascular smooth muscle cells following coinfection with Chlamydia pneumoniae and cytomegalovirus as a novel link between infection and atherosclerosis
Canadian Journal of Infectious Diseases & Medical Microbiology, 06/14/2012
Prochnau D et al. – The findings of the present study show that C pneumoniae and HCMV are able to act in synergy in coinfected AoSMC. The supra–additive induction of AoSMC growth factors and cytokines indicates a novel molecular link between infection and vascular disease development.