Hepcidin and erythropoietin measurements in the cord blood of neonates with meconium-stained amniotic fluid
Journal of Obstetrics and Gynaecology Research, 06/21/2012
Eryilmaz OG et al. – The authors demonstrated a significant relationship between erythropoietin levels and meconium passage, but failed to show the existence of a relationship between hepcidin levels and meconium passage.Methods
- A cross–sectional controlled study was conducted in secondary and tertiary care centers.
- ord blood samples of 40 neonates following term gestations (≥37weeks' gestation) with MSAF and 40 maternal age–, body mass index– and gravidity–matched controls with clear amniotic fluid were analyzed in this study.
- Demographic data, delivery outcomes and laboratory evaluations were recorded.
- Cord blood pH levels were lower in fetuses with MSAF when compared to those with clear amniotic fluid (P=0.0001).
- Fetuses with MSAF had higher cord blood erythropoietin levels in comparison to those with clear amniotic fluid (P=0.0001).
- Delivery outcomes and hepcidin measurements were similar in both groups.