Genome-wide Analysis of Central Corneal Thickness in Primary Open-angle Glaucoma Cases in the NEIGHBOR and GLAUGEN consortia
Investigative Ophthalmology & Visual Science, 06/04/2012
Clinical Article
Ulmer M et al. – The results suggest previously reported Central corneal thickness (CCT) loci are not significantly associated with primary open–angle glaucoma (POAG) susceptibility. By performing a quantitative analysis of CCT and a subsequent analysis of POAG, the authors identified single nucleotide polymorphisms in two cell adhesion molecules, NTM and CNTNAP4, which may increase POAG susceptibility in a subset of cases.



