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Adherence to Mediterranean diet reduces the risk of metabolic syndrome: A 6-year prospective study
Nutrition, Metabolism & Cardiovascular Diseases, 06/13/2012
Kesse–Guyot E et al. – All Mediterranean diet scores were associated in a potentially beneficial direction with components of MetS or MetS incidence. These findings support that individuals should be encouraged to follow a Mediterranean dietary pattern for reduction of MetS risk.
Methods- Subjects included were participants from the Supplementation en Vitamines et Minéraux AntioXydants (SU.VI.MAX) study.
- Adherence to Mediterranean diet was assessed using traditional Mediterranean diet score (MDS), an updated Mediterranean score (MED) and Mediterranean style–dietary pattern score (MSDPS) calculated from at least three 24–h records.
- In 3232 subjects, the association between Mediterranean diet scores and 6–y risk of MetS was evaluated.
- The association between Mediterranean scores and MetS components was also estimated. A lower risk of MetS was observed with increasing MED score (P–trend = 0.001) and MDS (P–trend = 0.03) in multivariate models.
- The adjusted odds ratios (95% Confidence Interval) for MetS risk were 0.47 (0.32–0.69) and 0.50 (0.32–0.77) in subjects in the highest versus lowest tertile of MED score and MDS, respectively.
- The MED score was inversely associated with waist circumference, systolic blood pressure and triglycerides, and directly associated with HDL–cholesterol.
- The MDS was negatively associated with waist circumference and triglycerides, and MSDPS was positively associated with HDL–cholesterol.
