Frequency, Genotype, and Clinical Spectrum of Best Vitelliform Macular Dystrophy: Data From a National Center in Denmark
American Journal of Ophthalmology, 05/30/2012
Bitner H et al. – The data expand the mutation spectrum of BEST1 in patients with Best disease. Alterations of the outer segments (OS) overlying lesions with subretinal fluid are similar to those seen in central serous retinopathy and may indicate impaired turnover of OS. The frequency estimate confirms that Best disease is one of the most common causes of early macular degeneration.