Smartest Doc
Asymmetric dimethylarginine in adults with cystathionine β-synthase deficiency
Atherosclerosis, 06/12/2012
Rocha MS et al. – Results showed that in CBS deficient patients with elevated levels of tHcy (median (total range): 33 (14–237)μmol/L), both ADMA and SDMA levels were normal. Moreover, tHcy and ADMA concentrations were not correlated (rs=0.017, p=0.94). These results favor the hypothesis that the negative vascular effects of HHcy have an ADMA–independent etiology.
