Use of Massively Parallel Pyrosequencing to Evaluate the Diversity of and Selection on Plasmodium falciparum csp T-Cell Epitopes in Lilongwe, Malawi
The Journal of Infectious Diseases, 05/24/2012
Bailey JA et al. – Authors saw evidence of weak variant–specific selection within this region of CS, suggesting naturally acquired immunity does induce variant–specific selection on CS. Therefore, the impact of CS vaccines on variant frequencies with widespread implementation of vaccination requires further study.