Preservation of Myocardial Structure Is Enhanced by Pim-1 Engineering of Bone Marrow Cells
Circulation Research, 05/25/2012
Quijada P et al. – Genetic modification of bone marrow stem cells (BMCs) with Pim–1 may serve as a therapeutic approach to promote recovery of myocardial structure. Future approaches may take advantage of salutary BMC actions in conjunction with other stem cell types to increase efficacy of cellular therapy and improve myocardial performance in the injured myocardium.