Dendritic Cells in Antifungal Immunity and Vaccine Design
Cell Host & Microbe, 05/21/2012
Roy RM et al. – Targeting DC may allow for the generation of potent vaccines against fungal pathogens. In the context of antifungal vaccine design, they describe the characteristics of the varied DC subsets, how DC recognize fungi, their function in immunity against fungal pathogens, and how DC can be targeted in order to create new antifungal vaccines. Ongoing studies continue to highlight the critical role of DC in antifungal immunity and will help guide DC–based vaccine strategies.