Corallopyronin A specifically targets and depletes essential obligate Wolbachia endobacteria from filarial nematodes in vivo Full Text
The Journal of Infectious Diseases, 05/16/2012
Clinical Article
Schiefer A et al. – The in vivo results showed that the antibiotic is effective against intracellular bacteria despite the many surfaces (blood vessels, pleural cavity membranes, worm cuticle) and membranes that must be crossed. Therefore, corallopyronin A is an antibiotic to develop further for filariasis elimination without concern for cross–resistance development in tuberculosis.



