Screening for Glucose-6-Phosphate Dehydrogenase Deficiency in Newborns--Practical Considerations
The Journal of Pediatrics, 05/30/2012
Watchko JF – Glucose–6–phosphate dehydrogenase (G6PD) deficiency is a common X–linked enzymopathy and noteworthy cause of severe neonatal hyperbilirubinemia and kernicterus worldwide. X–linkage of the G6PD gene results in hemizygous deficient males, homozygous deficient females, and a subset of affected heterozygous females via X–chromosome inactivation.



