Distinctive polysomnographic traits in nocturnal frontal lobe epilepsy
Parrino L et al. – Significant polysomnographic alterations seem to emerge in patients with Nocturnal frontal lobe epilepsy (NFLE) (increased rapid eye movement (REM) latency, epileptic fragmentation of slow wave sleep (SWS), and increase of CAP rate). The analysis of seizure distribution showed that most epileptic events occurred in SWS, with predominance in the first sleep cycle and decreasing in frequency together with the homeostatic decline of SWS across the night. Within the NREM sleep, CAP is a manifestation of unstable sleep and represents a powerful predisposing condition for the occurrence of nocturnal motor seizures, which arise in concomitance with a phase A.