Connecting mTORC1 signaling to SREBP-1 activation
Current Opinion in Lipidology, 05/30/2012
Bakan I et al. – The discovery of a connection between mTORC1 and SREBP–1 opens a new chapter in the understanding of the molecular mechanisms regulating de–novo lipogenesis. A better comprehension of these mechanisms is key for the development of new tools to treat NAFLD and its complications.