MicroRNAs: emerging roles in lipid and lipoprotein metabolism
Current Opinion in Lipidology, 05/30/2012
Sacco J et al. – Growing evidence support key roles for miRNAs in regulating both cholesterol and fatty acid metabolism, leading to considerable interest in miRNAs as potential drug targets to modulate lipid and lipoprotein metabolism. MiRNA–based therapeutics hold considerable promise in the fight to curtail the growing epidemic of obesity and type 2 diabetes and the associated risk of atherosclerosis.