Antitumoral activity of parvovirus-mediated IL-2 and MCP-3/CCL7 delivery into human pancreatic cancer: implication of leucocyte recruitment
Cancer Immunology, Immunotherapy, 05/14/2012
Dempe S et al. – The authors show here that activated NK and monocytic cells were found to be recruited by pancreatic ductal adenocarcinoma (PDAC) tumours upon infection with parvoviruses armed with IL–2 or the chemokine MCP–3/CCL7, resulting in a strong anti–tumour response.



