Antigen-specific T lymphocyte proliferation decreases over time in advanced chronic hepatitis C
Journal of Viral Hepatitis, 05/30/2012
Morishima C et al. – Lower levels of tetanus LP responses were associated with fibrosis progression and clinical outcomes (P = 0.009). Poorer CD4+ T cell proliferative function was associated with more advanced liver disease in chronic hepatitis C and may be further affected by long–term PEG–IFN treatment.