Evaluation of therapeutic effect of niacin and garlic combination on lipid profile and oxidants / antioxidants in psoriatic patients Full Text
Middle East Journal of Family Medicine, 05/16/2012
Alobaid AHA et al. – This study indicated that a combination of niacin and garlic was effective to restore dyslipedemia in patients with psoriasis and may prevent or modify atherosclerotic processes. The antioxidant constituents of garlic and niacin may act in a synergistic or additive fashion and protect cells against oxidative damage and protect against metabolic and cardiovascular changes in patients with psoriasis.Methods
- Blood lipid profile, Malondialdehyde and total antioxidant capacity were determined using commercial kits.
- The mean levels of serum lipids (triglyceride, very low density lipoprotein, low density lipoprotein, and total cholesterol) and Malondialdehyde in patients with psoriasis were found to be significantly reduced following treatment with a combination of Niacin and garlic.
- High density lipoprotein and total antioxidant capacity mean serum levels were significantly increased following the treatment course.