Studies on bacterial endotoxin and intestinal absorption function in patients with chronic heart failure
International Journal of Cardiology, 05/15/2012
Sandek A et al. – Active carrier–mediated intestinal transport is reduced in decompensated chronic heart failure (CHF) indicating epithelial dysfunction possibly as a consequence of intestinal ischemia. Higher LPS concentrations in edematous CHF relate to inflammation. LPS decreased after recompensation. This suggests a cause/effect relationship between edematous gut wall, epithelial dysfunction and translocating LPS.