Hotter BA et al. – High–risk ABCD2 score due to the impact of hemiparesis is associated with the occurrence of diffusion–weighted imaging (DWI) lesions but is still not accurate enough for a reliable differentiation of cerebrovascular events with and without MRI lesions.Methods
- TIA patients were prospectively enrolled in an observational MRI study to receive acute and follow-up stroke MRI.
- ABCD2 scores were calculated, and sociodemographics and risk factors were recorded.
- One hundred and thirty-two TIA patients were enrolled over nine months.
- Five patients were excluded due to different diagnosis.
- Forty-five of the 127 remaining patients showed acute ischemic lesions on DWI.
- Median ABCD2 scores for DWI-negative and -positive patients were 4 and 5, respectively.
- Ordinal, trichotomized and dichotomized ABCD2 were significantly associated to DWI.
- Univariate analysis of single score items and other risk factors demonstrated unilateral weakness, duration of symptoms and smoking as predictive for DWI restrictions.
- In multivariate analysis unilateral weakness remained significant. x