Pharmacokinetic profiles of epidural bupivacaine and ropivacaine following single-shot and continuous epidural use in young infants

Paediatric Anaesthesia, 04/24/2012

Epidural infusions of 0.2mg–1.kg–1.h–1 bupivacaine or ropivacaine appeared to be well tolerated and efficacious in this population. No accumulation of unbound drug concentrations occurred.

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