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Lower numbers of natural killer T cells in HIV-1 and Mycobacterium leprae co-infected patients
Immunology,
Carvalho KI et al. – The results suggest that Natural killer T (NKT) cells are decreased in frequency in HIV–1 and M. leprae co–infected patients compared with HIV–1 mono–infected patients alone, but are at a more activated state. Innate immunity in human subjects is strongly influenced by their spectrum of chronic infections, and in HIV–1–infected subjects, a concurrent mycobacterial infection probably hyper–activates and lowers circulating NKT cell numbers.
