Diagnosis of isolated high-grade prostatic intra-epithelial neoplasia: proposal of a nomogram for the prediction of cancer detection at saturation re-biopsy

BJU International, 04/30/2012

Prostate cancer (PCa) detection on saturation prostate re–biopsy (rPBx) after an initial diagnosis of high–grade prostatic intra–epithelial neoplasia (HGPIN) is significantly higher in patients with a ≤12–core initial prostate biopsy (PBx) than those with a >12–core initial PBx and in patients with pHGPIN than in those with mHGPIN. The authors developed a simple prognostic tool for the prediction of PCa detection in patients with initial HGPIN diagnosis who were undergoing saturation rPBx.

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