mdlinx mdlinx
Latest (498) Full Text Articles (11295) Article Summary

Anemia, Apnea of Prematurity, and Blood Transfusions
The Journal of Pediatrics,

Zagol K et al. – Blood transfusions are associated with decreased apnea in very low birth weight (VLBW) infants, and apneas are less frequent at higher hematocrits.

Methods
  • The authors continuously collected waveform, heart rate, and oxygen saturation data from patients in all 45 neonatal intensive care unit beds at the University of Virginia for 120 weeks.
  • Central apneas were detected using continuous computer processing of chest impedance, electrocardiographic, and oximetry signals.
  • Apnea was defined as respiratory pauses of >10, >20, and >30 seconds when accompanied by bradycardia (<100 beats per minute) and hypoxemia (<80% oxyhemoglobin saturation as detected by pulse oximetry).
  • In the transfusion cohort, waveforms were analyzed for 3 days before and after the transfusion for all VLBW infants who received a blood transfusion while also breathing spontaneously.
  • Mean apnea rates for the previous 12 hours were quantified and differences for 12 hours before and after transfusion were compared.
  • In the hematocrit cohort, 1453 hematocrit values from all VLBW infants admitted and breathing spontaneously during the time period were retrieved, and the association of hematocrit and apnea in the next 12 hours was tested using logistic regression.

Results
  • Sixty-seven infants had 110 blood transfusions during times when complete monitoring data were available.
  • Transfusion was associated with fewer computer-detected apneic events.
  • Probability of future apnea occurring within 12 hours increased with decreasing hematocrit values.

Please login or register to follow this author.
Are you sure you want to Unfollow this Author?
► Click here to access PubMed, Publisher and related articles...
<< Previous Article | Next Article >>

    Currently, there are no available articles.

Your Unread Messages in Medical Student

See All >> Messages include industry-sponsored communications and special communications from MDLinx

Most Popular Medical Student Articles

Last month's top read Top Articles of 2013

Indexed Journals in Medical Student: Academic Medicine, BMC Medical Education, Medical Teachermore

Other Topics in Medical Student

Register now to view all the MDLinx contents (FREE)!

  • Stay current on the latest literature, research and clinical news
  • Get special communications and offers from MDLinx and our sponsors
  • Receive invitations to paid market research
View Samples and Register

Stay current - Media Tool

Newsletter
RSS
Follow
Like

Receive the latest mecial news
updates for free via email

Sign up!

Subscribe to our free RSS feeds:

Get the latest news in your specialty automatically added to your newsreader or your personal My Yahoo!, Google, My MSN or My AOL page. Learn More

Close