No evidence of somatic DNA copy number alterations in eutopic and ectopic endometrial tissue in endometriosis
Human Reproduction, 04/13/2012
Saare M et al. – In the present study no endometriosis–specific SCNAs or regions of cn–LOH in eutopic or ectopic endometrium were found. Nevertheless, as aythors studied only 17 endometriotic tissues derived from 11 patients they cannot entirely exclude the occurrence of rare SCNAs. Based on the results they suggest that molecular mechanisms other than chromosomal rearrangements most likely underlie the onset and progression of endometriosis.