Correlation of LINE-1 Methylation Levels in Patient-Matched Buffy Coat, Serum, Buccal Cell, and Bladder Tumor Tissue DNA Samples

Cancer Epidemiology, Biomarkers & Prevention, 06/08/2012

The mean promoter LINE–1 %5MeC measurements were correlated between buffy coat and serum DNA samples. No correlation was observed between genomic DNA sources and tumor tissues; however a significant inverse association between tumor percent LINE–1 methylation and tumor stage/grade was found.

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