Monitoring seasonal influenza A evolution: Rapid 2009 pandemic H1N1 surveillance with an reverse transcription-polymerase chain reaction/electro-spray ionization mass spectrometry assay

Journal of Clinical Virology, 06/08/2012

This comparison of early versus late influenza samples analyzed by RT–PCR/ESI–MS demonstrates the influenza typing assay's ability as a universal influenza detection platform to provide high–fidelity pH1N1 strain identification over time, despite increasing genetic diversity in the circulating virus. The genotyping data can also be leveraged for high–throughput influenza surveillance.

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