Patch testing with the textile dyes Disperse Orange 1 and Disperse Yellow 3 and some of their potential metabolites, and simultaneous reactions to para-amino compounds

Contact Dermatitis, 06/04/2012

The authors show that it is possible that the major sensitizers in contact allergy to DO1 and DY3 are their metabolites, p–aminodiphenylamine and 2–amino–p–cresol, respectively, which might be formed by the azoreductase pathway of skin bacteria.

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