Effects of integrin-linked kinase on human corpus cavernosum smooth muscle cell cytoskeletal organisation

Andrologia, 05/24/2012

The results show that the targeting of integrin–linked kinase (ILK) with small interfering RNA significantly inhibited cell attachment, spreading, migration and microfilament dynamics in human corpus cavernosum smooth muscle cells. These findings indicate that ILK might be a potential therapeutic molecular target for the treatment of erectile dysfunction.

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