Uncovering the source of new benzodiazepine prescriptions in community-dwelling older adults
International Journal of Geriatric Psychiatry, 05/10/2012Halme AS et al.
Interventions are required to curb incident benzodiazepine prescriptions at their source both in hospitals and in ambulatory care settings.
Data were derived from 1189 community-dwelling adults aged 65 years naive to benzodiazepine consumption, enrolled in the Étude sur la Santé des Aines, a prospective 3-year cohort study conducted in Québec, Canada.
Health survey questionnaires were linked with provincial administrative databases of prescription and health service claims.
Analysis with multivariate Poisson regression models compared the risk of incident benzodiazepine use post-hospitalization versus after an ambulatory care visit.
Models were adjusted for sex, age, antidepressant use, and concomitant drugs.
Sub-analyses were conducted for chronic prescriptions.
Incident benzodiazepine use was 11% over a 2-year period, with 18.3% of prescriptions leading to chronic use (> 90 days).
Hospitalization conferred a 2.7-fold greater risk of incident use than an outpatient visit (OR 2.66, 95% CI 1.78-3.98) and a 4.7-fold (OR 4.74, 95% CI 1.63-13.78) increased risk of chronic use, after adjusting for potential confounders.
Despite the increased risk, only 13% of new prescriptions originated post-hospital discharge, with the remainder prescribed during outpatient visits.
MDLinx connects healthcare professionals and patients to tomorrow's important medical news, while providing the pharmaceutical and healthcare industries with highly targeted interactive marketing, education, content, and medical research solutions.