Differential manifestations of prepubescent, pubescent and postpubescent pediatric patients with systemic lupus erythematosus: A retrospective study of 96 Chinese children and adolescents

Pediatric Rheumatology, 05/03/2012

Age at disease onset is related to initial manifestations in pediatric systemic lupus erythematosus (SLE) patients at the center. Certain parameters such as renal involvement, splenomegaly, low C3 level, low C4 level, lymphopenia, leukopenia, and anti–Sm & anti–Jo–1 antibody were found to be significantly different among the age groups. Renal involvement might be the key symptom that varies with age.

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