ABCD2 as a Screening Tool for Cerebral Infarction on Stroke MRI

European Neurology, 04/30/2012

High–risk ABCD2 score due to the impact of hemiparesis is associated with the occurrence of diffusion–weighted imaging (DWI) lesions but is still not accurate enough for a reliable differentiation of cerebrovascular events with and without MRI lesions.

Methods

  • TIA patients were prospectively enrolled in an observational MRI study to receive acute and follow-up stroke MRI.
  • ABCD2 scores were calculated, and sociodemographics and risk factors were recorded.

Results

  • One hundred and thirty-two TIA patients were enrolled over nine months.
  • Five patients were excluded due to different diagnosis.
  • Forty-five of the 127 remaining patients showed acute ischemic lesions on DWI.
  • Median ABCD2 scores for DWI-negative and -positive patients were 4 and 5, respectively.
  • Ordinal, trichotomized and dichotomized ABCD2 were significantly associated to DWI.
  • Univariate analysis of single score items and other risk factors demonstrated unilateral weakness, duration of symptoms and smoking as predictive for DWI restrictions.
  • In multivariate analysis unilateral weakness remained significant.
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