Chromophobe renal cell carcinoma with prolonged response to targeted therapy: a case report

Journal of Medical Case Reports, 04/24/2012

The authors present the case of a 43–year–old Caucasian man with advanced chromophobe renal cell carcinoma treated with the tyrosine kinase inhibitor sunitinib and subsequently with sorafenib and the mammalian target of the rapamycin inhibitor everolimus, achieving a prolonged response and significant clinical benefit. The authors report an unexpectedly high efficacy of everolimus as a third–line treatment in a patient with metastatic chromophobe renal cell carcinoma.

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