Tuberculosis seasonality in the Netherlands differs between natives and non-natives: a role for vitamin D deficiency

The International Journal of Tuberculosis and Lung Disease, 04/18/2012

A seasonal peak in TB notifications is apparent in non–natives, but is absent in natives. This peak is driven by the seasonality of extra–pulmonary TB [EPTB]) notifications, which are highest in June–July. The contribution of winter crowding is discussed. Vitamin D deficiency, enhancing disease development at the end of winter–early spring, seems the most likely factor explaining the yearly peak in EPTB.

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