Subclinical hypothyroidism, mood, and cognition in older adults: a review

International Journal of Geriatric Psychiatry, 03/29/2012

It remains unclear whether subclinical hypothyroidism (SCH) leads to significant mood and cognitive impairments in most older patients. More research is required to determine the nature and extent of this association and whether thyroid hormone replacement therapy is appropriate and effective in treating SCH–associated neurobehavioral impairments.

Methods

  • A comprehensive literature review.

Results

  • It remains unclear whether SCH leads to significant mood and cognitive impairments in most older patients.
  • More research is required to determine the nature and extent of this association and whether thyroid hormone replacement therapy is appropriate and effective in treating SCH-associated neurobehavioral impairments.

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