Serum matrix metalloproteinase 9 and colorectal neoplasia: a community-based evaluation of a potential diagnostic test

British Journal of Cancer, 03/21/2012

The authors demonstrated a significant association between serum matrix metalloproteinase (MMP9) concentration and the presence of neoplasia. Serum MMP9 levels are raised in those with cancer and high–risk adenomas, although MMP9 estimation is likely to have the greatest predictive utility when used as part of a panel of biomarkers. Further work is required to identify biomarkers that are sufficiently accurate for implementing into routine practice.

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