Effects of Tomato- and Soy-Rich Diets on the IGF-I Hormonal Network: A Crossover Study of Postmenopausal Women at High Risk for Breast Cancer

Cancer Prevention Research, 05/10/2011

The tomato–rich diet had little effect on cell–signaling biomarkers previously associated with breast cancer risk.Increased soy protein intake may lead to small, but significant, increases in insulin–like growth factor (IGF)– and IGF–binding protein (IGFBP)–3. Soy consumption also led to a significant decrease in sex hormone–binding globulin (SHBG), which has been hypothesized to promote, rather than prevent, cancer growth.

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