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Discovery of a new role of human resistin in hepatocyte low-density lipoprotein receptor suppression mediated in part by proprotein convertase subtilisin/kexin type 9

Melone M et al. – These results reveal for the first time that resistin is a highly attractive therapeutic target in ameliorating elevated serum low–density lipoprotein and, thereby, atherosclerotic cardiovascular diseases in obese humans. [more...]

JACC - Journal of the American College of Cardiology

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