The Latest Articles
Access the latest medical articles in your specialty▶ See the LATEST ARTICLES
The Conference Center
Discover medical conferences through maps, event descriptions, conference coverage, and interviews.▶ Visit the Conference Center
The Clinical Trial Navigator
Find Clinical Trials by Location, Trial Phase, and Ratings.▶ Locate Clinical Trials
The Mobile App Center
Read our unbiased reviews of medical apps▶ Visit the Mobile App Center
The Product Center
Get the latest information on new drugs, equipment, devices, and procedures▶ Visit the Product Center
Are You the Smartest Doc in America?
Sharpen your clinical knowledge and compete with other physicians▶ Play Today's Quiz
Review 1000s of questions based on clinical literature and track your progress over time▶ Try Physician Review
Are You Prepared for the Boards?
Prepare for board reviews with confidence with 1000s of board exam style questions▶ Be Ready with Board Exam Prep
Apply and track your progress.▶ Search Job Openings
Post your CV to allow recruiters and employers to contact you about new job opportunities▶ Post Your CV
Search our comprehensive hospital listings▶ Search Hospital Listings
More Physicians. More Candidates.
Your job is hard. Finding the RIGHT physician should not be.▶ Enter Employers
Carretero R et al. – The authors favor the idea that the major factor determining the success or failure of immunotherapy is the nature of HLA Class I alterations in tumor cells and not the type of immunotherapy used. If the molecular alteration is reversible by the immunotherapy, the HLA expression will be upregulated and the lesion will be recognized and rejected. In contrast, if the defect is structural the MHC Class I expression will remain unchanged and the lesion will progress. [more...]
2015 © M3 USA. ALL Rights Reserved.