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See Latest ArticlesEffects of the Gastrin-Releasing Peptide Antagonist RC-3095 in a Model of Ulcerative Colitis
Digestive Diseases and Sciences, 11/10/09
Damin DC et al. – RC–3095 reduced the colitis severity in a well–established experimental model of IBD. The anti–inflammatory activity of this compound was associated with a reduction in the colonic expression of TNF–alpha. These results suggest that interference with GRP pathway might represent a potential new strategy for the treatment of ulcerative colitis that deserves further investigational studies.
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