Internal Med Medical News about Angiotensin II Type 1 Receptor Blockers

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Comparative assessment of angiotensin receptor blockers in different clinical settings
Vascular Health and Risk Management, 11/09/09

Verdecchia P et al. – Convincing evidence accumulated over the last decade that therapeutic intervention with angiotensin receptor blockers (ARBs) is effective to slow down or block the progression of cardiovascular disease at different steps of the continuum, with measurable clinical benefits. However, despite the shared mechanism of action, each ARB is characterized by specific pharmacological properties that may influence its clinical efficacy. Indeed, important differences among available ARBs emerged from clinical studies. Therefore, generalization of results obtained with a specific ARB to all available ARBs may be misleading. The present review provides a comparative assessment of the different ARBs in their efficacy on major clinical end–points along the different steps of the cardiovascular disease continuum.

Significance of initial blood pressure and comorbidity for the efficacy of a fixed combination of an angiotensin receptor blocker and hydrochlorothiazide in clinical practice
Vascular Health and Risk Management, 11/13/09 Relevance Score: 96%

Are Angiotensin-Converting Enzyme Inhibitors and Angiotensin Receptor Blockers Especially Useful for Cardiovascular Protection?
Journal of the American Board of Family Medicine, 11/09/09 Relevance Score: 96%

Systematic Review: Comparative Effectiveness of Angiotensin-Converting Enzyme Inhibitors or Angiotensin II-Receptor Blockers for Ischemic Heart Disease
Annals of Internal Medicine, 10/20/09 Relevance Score: 96%

Effects of angiotensin II type 1 receptor blocker on ambulatory blood pressure variability in hypertensive patients with overt diabetic nephropathy
Hypertension Research, 11/09/09 Relevance Score: 95%

Angiotensin-converting enzyme and angiotensin II receptor subtype 2 genotypes in type 1 diabetes and severe hypoglycaemia requiring emergency treatment: a case cohort study
Pharmacogenetics and genomics, 10/26/09 Relevance Score: 93%