Internal Med Medical News about Ischemic Attack, Transient

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Transient Ischemic Attack after Tissue Plasminogen Activator: Aborted Stroke or Unnecessary Stroke Therapy
Cerebrovascular Diseases, 11/11/09

Uchino K et al. – Over 10% of patients who receive tPA for cerebral ischemia do not develop ischemic injury. tPA use for a nonischemic process is infrequent but is associated with community hospital use.

Exclusive Author Commentary
Ken Uchino, 11/11/09

Over 10% of patients who receive intravenous tPA thrombolysis for presumed cerebral ischemia do no develop ischemic injury clinically or on brain imaging. Most of such excellent outcome is appear to be due to true transient ischemic event due to thrombolysis and "averting a stroke." As expected, such patients had milder stroke symptoms and lower glucose. Only a small portion, 3.5% of overall thrombolysis, are treatments that were likely not brain ischemia. Such stroke mimics are infrequent but were more common in community hospitals. As with any disease in emergent settings, there is an inherent diagnostic uncertainty. Whether the rate of stroke mimics is acceptable is a matter of opinion.

Computed tomography and computed tomography angiography findings predict functional impairment in patients with minor stroke and transient ischaemic attack
International Journal of Stroke, 11/13/09 Relevance Score: 80%

Brain natriuretic peptide as a predictor of delayed atrial fibrillation after ischaemic stroke and transient ischaemic attack
European Journal of Neurology, 11/04/09 Relevance Score: 80%

MRI Detection of New Microbleeds in Patients With Ischemic Stroke. Five-Year Cohort Follow-Up Study
Stroke, 11/11/09 Relevance Score: 79%

Low Ankle-Brachial Index Predicts Cardiovascular Risk After Acute Ischemic Stroke or Transient Ischemic Attack
Stroke, 10/20/09 Relevance Score: 79%

Ischemic tolerance in stroke treatment
Expert Review of Cardiovascular Therapy, 10/16/09 Relevance Score: 79%