Internal Med Medical News about Pain Pruritus

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Itch and pain
Neuroscience & Biobehavioral Reviews, 11/05/09

Schmelz M – In this review the authors describe itch–specific pathways, but also evidence for a modified pattern theory of pruritus offering independent mechanisms for the itch induction. Traditionally pain and itch have been regarded as antagonistic as painful stimuli such as scratching suppress itch and opioids suppress pain, but generate itch. However, concerning mechanisms of sensitization to itch or pain, surprisingly similar patterns have been observed lately in both inflamed tissue and in the spinal cord. These similarities open up two highly interesting perspectives: the role of well established analgesic therapeutic concepts can be validated in chronic itch conditions and on the other hand investigations of sensitization in easily accessible pruritic skin may help to validate concepts of nociception in humans. These perspectives illustrate that itch and pain research no longer follows separate paths, but can be advantageously interconnected.

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Analysis of individual patient data from clinical trials: epidural morphine for postoperative pain
British Journal of Anesthesia, 11/05/09 Relevance Score: 66%

The relationship between disease activity, sleep, psychiatric distress and pain sensitivity in rheumatoid arthritis: A cross-sectional study
Arthritis Research & Therapy, 11/03/09 Relevance Score: 49%

Pain among Veterans of Operations Enduring Freedom and Iraqi Freedom: Do Women and Men Differ?
Pain Medicine, 10/13/09 Relevance Score: 49%

Prognosis for patients with chronic low back pain: inception cohort study
British Medical Journal, 10/09/09 Relevance Score: 49%

Corticosteroid Injection Treatment to the Ischiadic Spine Reduced Pain in Women With Long-Lasting Sacral Low Back Pain With Onset During Pregnancy: A Randomized, Double Blind, Controlled Trial
Spine, 10/01/09 Relevance Score: 49%